<p>&nbsp;</p>

<p>BREASTFEEDING</p>

<p>DONETAZ SR 11.5MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/driving_and_using_machines.jpg" /></p>

<p>DRIVING AND USING MACHINES</p>

<p>DONETAZ SR 11.5MG TABLET may cause tiredness, dizziness and muscle cramp which could affect your ability to drive or operate machines. If you experience these side effects, do not drive or operate machines. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/alcohol.jpg" /></p>

<p>ALCOHOL</p>

<p>Avoid consumption of alcohol while taking DONETAZ SR 11.5MG TABLET because it may alter the effect of this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/kidney.jpg" /></p>

<p>KIDNEY</p>

<p>DONETAZ SR 11.5MG TABLET should be used with caution in patients with mild kidney disease. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/liver.jpg" /></p>

<p>LIVER</p>

<p>DONETAZ SR 11.5MG TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with liver problems or hepatitis. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/allergy.jpg" /></p>

<p>ALLERGY</p>

<p>Do not take DONETAZ SR 11.5MG TABLET if you are allergic to Donepezil or piperidine derivatives such as haloperidol, thioridazine, or any of the other ingredients of this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/lungs.jpg" /></p>

<p>LUNGS</p>

<p>DONETAZ SR 11.5MG TABLET should be used with caution in patients with asthma or long-term lung disease. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/heart_disease.jpg" /></p>

<p>HEART DISEASE</p>

<p>DONETAZ SR 11.5MG TABLET should be used with caution in patients with heart diseases such as irregular or very slow heartbeat, fast heartbeat, abnormal heart rhythms, family history of prolonged QT interval (fast and chaotic heartbeats), had heart failure, or heart attack. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<h2>OTHERS</h2>

<p>Before taking DONETAZ SR 11.5MG TABLET, inform your doctor if you:&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</p>

<ul>
<li>Have low levels of magnesium or potassium in your blood</li>
<li>Have difficulty passing urine</li>
<li>Have stomach or duodenal ulcers</li>
<li>Have seizures (fits) or convulsions</li>
</ul>

<p><strong>Use in pediatrics:</strong></p>

<p>The safety and effectiveness of DONETAZ SR 11.5MG TABLET in pediatric patients have not been established. Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<p><strong>Use in geriatrics:</strong></p>

<p>DONETAZ SR 11.5MG TABLET should be used with caution in elderly patients (aged 65 years above). Consult your doctor before taking DONETAZ SR 11.5MG TABLET.</p>

<h2>INTERACTIONS</h2>

<p><strong>A. Drug-Drug Interactions:</strong></p>

<p>Before taking DONETAZ SR 11.5MG TABLET, inform your doctor, if you are taking any of the following medicine:</p>

<ul>
<li>Medicines used for heart rhythm problems (Ex. amiodarone, sotalol)</li>
<li>Medicines used for depression (Ex. citalopram, escitalopram, amitriptyline, fluoxetine)</li>
<li>Medicines used for psychosis (Ex. pimozide, sertindole, ziprasidone)</li>
<li>Medicines used for bacterial infections (Ex. clarithromycin, erythromycin, levofloxacin, moxifloxacin, rifampicin)</li>
<li>Medicines used for fungal infections (Ex. ketoconazole)</li>
<li>Other medicines used to treat Alzheimer&rsquo;s disease (Ex. galantamine)</li>
<li>Medicines used for arthritis (Ex. aspirin, non-steroidal anti-inflammatory (NSAID) drugs such as ibuprofen, or diclofenac sodium)</li>
<li>Anticholinergics medicines (Ex. tolterodine)</li>
<li>Anticonvulsants (Ex. phenytoin, carbamazepine)</li>
<li>Medicines used to treat heart condition (Ex. quinidine, beta-blockers such as propanolol and atenolol)</li>
<li>Muscle relaxants (Ex. diazepam, succinylcholine)</li>
<li>General anesthetics (Ex. propofol, ketamine, thiopental)</li>
<li>Medicines obtained without a prescription (Ex. herbal remedies)</li>
</ul>

<p><strong>Overdosage:</strong></p>

<p>If you or anyone else accidentally takes too much of DONETAZ SR 11.5MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling and being sick, drooling, sweating, slow heart rate, low blood pressure (lightheadedness or dizziness when standing), breathing problems, losing consciousness and seizures (fits) or convulsions.</p>

<h2>SYNOPSIS</h2>

<table border="0" cellpadding="1" cellspacing="1">
<tbody>
<tr>
<td><strong>Drug</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Donepezil</td>
</tr>
<tr>
<td><strong>Pharmacological Category</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Acetyl cholinesterase Inhibitor</td>
</tr>
<tr>
<td><strong>Therapeutic Indication</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Alzheimer disease</td>
</tr>
<tr>
<td><strong>Dosage Forms</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Tablet, Syrup, Orally disintegrating strips</td>
</tr>
</tbody>
</table>

<h2>MORE INFORMATION</h2>

<ul>
<li>Keep the medicine out of reach in children</li>
<li>Store DONETAZ SR 11.5MG TABLET at room temperature</li>
</ul>

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