JANKEY M 1000 TABLET is a combination of Metformin and Sitagliptin which belongs to the group of medicines called Antidiabetic agents. It is used to control blood sugar levels in patients with Type II diabetes mellitus along with proper diet and exercise.

 

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

 

Before taking JANKEY M 1000 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have high blood cholesterol levels, severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently.

 

During therapy with JANKEY M 1000 TABLET, your doctor might regularly monitor your blood sugar levels and kidney functions to avoid the risk of unwanted side effects. He might also ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption to achieve better results.

 

JANKEY M 1000 TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism, shock or problems in breathing or blood circulation.

Consult your doctor before taking JANKEY M 1000 TABLET if you are pregnant or breastfeeding. The most common side effects of taking JANKEY M 1000 TABLET are low blood sugar levels, stomach upset, constipation, flatulence, metallic taste in mouth, sore throat, stuffy nose and joint pain. Consult your doctor if they bother you.

 

USES OF JANKEY M 1000 TABLET


Treats Type II diabetes mellitus


 

HOW JANKEY M 1000 TABLET WORKS

JANKEY M 1000 TABLET is an antidiabetic medicine. It contains two medicines namely metformin and sitagliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absoprtion in the body.

Sitagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, JANKEY M 1000 TABLET controls blood sugar levels and improve glycemic control in patients with type II diabetes.

 

DIRECTIONS FOR USE

Take JANKEY M 1000 TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking JANKEY M 1000 TABLET unless your doctor advice you to stop.

 

SIDE EFFECTS OF JANKEY M 1000 TABLET

COMMON


Hypogylcemia (low blood sugar)
Nausea, vomiting
Flatulence, diarrhea, constipation, stomach pain, loss of appetite
Swelling of hands and legs (edema)
Upper respiratory infections
Stuffy nose, sore throat
Joint pain, pain in arms or legs
Metallic taste


 

UNCOMMON


Drowsiness, dizziness
Dry mouth
Headache
Skin itching


 

RARE

Stop taking JANKEY M 1000 TABLET and consult your doctor immediately if you experience any of the following side effects:


Serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
Severe blistering of the skin (signs of an allergic skin reaction called bullous pemphigoid)
Signs of pancreatitis (severe and persistent pain in the stomach areas which might reach through to your back with or without nausea and vomiting)
Signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)


 

HOW TO MANAGE SIDE EFFECTS

Hypoglycemia (low blood sugar levels)

Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack or a drink and check your blood sugar levels once again. Contact your doctor if there is no improvement in your condition.

 

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

 

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

 

Constipation:

Taking JANKEY M 1000 TABLET with meals may reduce the chances of constipation. However, if you experience constipation, eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

 

WARNING & PRECAUTIONS



PREGNANCY

JANKEY M 1000 TABLET is not recommended for use in pregnant women. Therefore, inform your doctor before taking JANKEY M 1000 TABLET if you are pregnant, think you may be pregnant or planning to have a baby.



BREASTFEEDING

JANKEY M 1000 TABLET is not recommended for use in breastfeeding women. However, consult your doctor before taking it.



DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy after taking JANKEY M 1000 TABLET.



ALCOHOL

Avoid consumption of alcohol while taking JANKEY M 1000 TABLET as it may increase the risk of unwanted side effects.



KIDNEY

JANKEY M 1000 TABLET is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.



LIVER

JANKEY M 1000 TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gall stones. Therefore, consult your doctor before taking it.



ALLERGY

Do not take JANKEY M 1000 TABLET if you are allergic to Metformin or Sitagliptin.



HEART DISEASE

JANKEY M 1000 TABLET is not recommended for use in patients with severe heart problems (such as acute heart failure or a recent heart attack). Therefore, consult your doctor before taking it.

 

OTHERS

JANKEY M 1000 TABLET is not recommended for use if you:


Have severe, uncontrollable diabetes
Have nausea, vomiting, diarrhea or rapid weight loss
Have lactic acidosis or ketoacidosis (buildup of lactic acid or ketones in the body)
Are dehydrated (due to drinking less fluid or had severe vomiting or diarrhea during the recent days)
Have any severe systemic infection
Have shock or problems in blood circulation
Have problems in breathing
Are an alcoholic
Are scheduled for any X-rays in the upcoming days


Before taking JANKEY M 1000 TABLET, inform your doctor if you:


Have or ever had pancreatitis (inflammation of the pancreas)
Have alcohol dependence
Have high blood lipids levels
Have type I diabetes mellitus (insulin-dependent diabetes)
Are about a have a major surgery
Are in fasting
Are malnourished, starved, on an irregular diet or feeling weak
Perform extreme muscle exercises
Have Vitamin B12 deficiency


 

Use in Pediatrics:

JANKEY M 1000 TABLET is not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.

 

Use in Geriatrics:

JANKEY M 1000 TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.

 

INTERACTIONS

A. Drug - Drug interactions:

Before taking JANKEY M 1000 TABLET, inform your doctor if you are taking any of the following medicines such as:


Other medicines used to treat diabetes (Ex. glimepiride, glyburide, gliclazide, teneligliptin, rosiglitazone, pioglitazone)
Iodine contrast medium (used during X-rays)
Medicines used to treat asthma (Ex. salbutamol or terbutaline)
Corticosteroids (used to treat pain and inflammation) Ex. hydrocortisone, prednisolone
Diuretics (used to reduce edema and to treat hypertension) Ex. furosemide, hydrochlorothiazide
Medicines used to treat pain and inflammation (such as ibuprofen and celecoxib)
Medicines used to treat high blood pressure (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
Alcohol containing medicines (such as cough syrups)
Cimetidine (a medicine used to treat stomach ulcer)
Dolutegravir (a medicine used to treat HIV infection)
Ranolazine (a medicine used to treat chest pain)
Trimethoprim (a medicine used to treat bacterial infection)
Digoxin (a medicine used to treat irregular heartbeat)


 

Overdosage:

If you or anyone else accidentally took more JANKEY M 1000 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold or uncomfortable, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.

 

SYNOPSIS




Drug
:  
Metformin, Sitagliptin


Pharmacological Category
:  
Biguanides, DPP-4 Inhibitors


Therapeutic Indication
:  
Type II Diabetes mellitus


Dosage Forms
:  
Tablet, Capsule, Combipack




 

MORE INFORMATION


Keep JANKEY M 1000 TABLET out of the sight and reach of children
Store JANKEY M 1000 TABLET below 30°C