FACILOC 80MG INJECTION contains Enoxaparin which belongs to the group of medicines called Anticoagulants. It is used to treat and prevent blood clot formation in the body.

FACILOC 80MG INJECTION works by stopping the blood clots formation. It also prevents the existing blood clots from growing bigger in size. Due to this property, it is highly used as a prophylactic therapy for preventing blood clot formation during risky conditions that involves clot formation such as before or after a surgery, during dialysis or after a heart attack or a severe chest pain (angina).

It can also be used to reduce the risk of blood clot formation caused due to prolong period of immobility or due to cancer therapy.

Before receiving FACILOC 80MG INJECTION inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have diabetes, high blood pressure or a history of stomach ulcer.

FACILOC 80MG INJECTION is not recommended for use in patients who are bleeding heavily or have any pre-existing conditions (such as stomach ulcer or stroke) that can increase the risk of internal bleeding. It is also not suitable for use in patients scheduled for spinal anesthesia or lumbar puncture.

Inform your doctor before receiving FACILOC 80MG INJECTION if you are pregnant or breastfeeding. The most common side effects of receiving FACILOC 80MG INJECTION are injection site reactions (such as pain or irritation), skin rashes, low platelet count, bleeding or bruising and headache. Consult your doctor if any of these side effect worsens.

USES OF FACILOC 80MG INJECTION


Treats and prevents blood clots in the body


HOW FACILOC 80MG INJECTION WORKS

FACILOC 80MG INJECTION is an anticoagulant medicine. It inactivates certain proteins (such as coagulation factor II a and X a) in the blood that causes blood clotting. This reduces the chances of blood clot formation within the body which therefore prevents blockage of blood vessels.

DIRECTIONS FOR USE

FACILOC 80MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously) or under the skin (subcutaneously).

It can also be self-administered by the patients if advised by the physician. Carefully, follow the instructions given by the doctor in case of self-administration.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF FACILOC 80MG INJECTION

COMMON


Bleeding, bruising
Injection site reactions (such as pain or redness)
Pinky patches on the skin (especially in the injection site)
Skin rash, itching, redness
Low RBC count in blood
Headache


UNCOMMON


Sudden severe headache
Tender and swollen stomach


RARE


Increased blood potassium levels
Hair loss
Osteoporosis (weak and brittle bones)
Tingling, numbness and muscular weakness (especially in the lower part of the body) especially if you have had a spinal puncture or a spinal anesthetic
Loss of control over the intestine or bladder


Contact your doctor immediately if you experience any of the following side effects after receiving FACILOC 80MG INJECTION:


Severe allergic reactions (such as skin rash, itching, swelling of the face, mouth, throat, tongue leading to difficulty in breathing or swallowing)
Signs of excessive bleeding (excessive weakness, tiredness, paleness, dizziness, headache or unexplained swelling)
Severe skin reactions (such as skin rash, itching, skin redness with blisters or peeling of the skin, which may be associated with high fever and joint pains, dark red spots under the skin)
Cramping pain, redness, warmth, swelling in one of the legs
Breathlessness, chest pain, coughing up blood


HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Injection site reactions:

Place an ice pack on the affected area. Do not frequently move the injection site. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS



PREGNANCY

FACILOC 80MG INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor before receiving it.



BREASTFEEDING

FACILOC 80MG INJECTION should be used with caution in breastfeeding women. Therefore, consult your doctor before receiving it.



DRIVING AND USING MACHINES

FACILOC 80MG INJECTION does not affect your ability to drive or operate machinery. However, do not drive or handle any heavy tools or machines if your ability is affected by FACILOC 80MG INJECTION.



ALCOHOL

Avoid consumption of alcohol before receiving FACILOC 80MG INJECTION.



KIDNEY

FACILOC 80MG INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.



LIVER

FACILOC 80MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.



ALLERGY

Talk to your doctor before receiving FACILOC 80MG INJECTION if you are allergic to Enoxaparin or to any other low molecular weight heparins (such as nadroparin, tinzaparin or dalteparin).



HEART DISEASE

FACILOC 80MG INJECTION should be used with caution in patients fitted with heart valves and in patients with heart problems (such as heart infections or high blood pressure). Therefore, consult your doctor before receiving it.

OTHERS

FACILOC 80MG INJECTION is not recommended for use if you:


Have a previous history of heparin-induced thrombocytopenia (low platelet count in blood)
Have antibodies against enoxaparin in your blood
Are bleeding heavily
Have any internal condition that can increase the risk of heavy bleeding (such as stomach ulcer, stroke, surgery)
Are scheduled for any spinal procedures (such as spinal anesthesia or lumbar puncture)


Before receiving FACILOC 80MG INJECTION, inform your doctor if you:


Have a history of stomach ulcers
Recently had stroke
Have diabetes
Have diabetic retinopathy (eye damage caused due to diabetes)
Recently had surgery on your brain or eyes
Are underweight or overweight
Have hyperkalemia (high blood potassium levels)


Use in pediatrics:

The safety and effectiveness of FACILOC 80MG INJECTION have not been established in children and adolescents (aged below 18 years). Your doctor will decide about administering FACILOC 80MG INJECTION to your child after evaluating the risks and benefits of the therapy.

Use in geriatrics:

FACILOC 80MG INJECTION should be used with caution in elderly patients (aged 65 years or older). Therefore, consult your doctor before receiving it.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving FACILOC 80MG INJECTION, inform your doctor if you are taking any of the following medicines:


Warfarin (a medicine used for blood thinning)
Other medicines used to stop blood clots from forming (Ex. aspirin, clopidogrel, dipyridamole)
Dextran injection (used to replace blood)
Medicines used to relieve pain and swelling (Ex. ibuprofen, diclofenac, ketorolac, tromethamine)
Medicines used to treat asthma, rheumatoid arthritis, and other conditions (Ex. prednisolone, dexamethasone)
Medicines that increase blood potassium levels (Ex. spironolactone, triamterene, amiloride)
Sulfinpyrazone (used to prevent gout)


Overdosage:

FACILOC 80MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.

SYNOPSIS




Drug
:  
Enoxaparin


Pharmacological Category
:  
Parenteral Anticoagulants


Therapeutic Indication
:  
Blood clots


Dosage Forms
:  
Injection, Pre-filled syringes (PFS), Pen, Cartridge




MORE INFORMATION


Keep FACILOC 80MG INJECTION out of reach of children
Store FACILOC 80MG INJECTION at room temperature