<p>&nbsp;</p>

<p>Headache</p>

<p>Avoid bright lights, take enough rest and drink more water. Consult your doctor if any of your symptoms get worse or persist.</p>

<p><img src="https://www.netmeds.com/images/content/icons/nausea_and_vomiting.jpg" /></p>

<p>Nausea And Vomiting</p>

<p>Stick to simple meals. Avoid eating oily or spicy meals.<strong>&nbsp;</strong>Consult your doctor if any of your symptoms get worse or persist.</p>

<p><img src="https://www.netmeds.com/images/content/icons/stomach_pain.jpg" /></p>

<p>Stomach Pain</p>

<p>Try to rest and relax. Eat and drink slowly. Keep a heating pad. Consult your doctor if any of your symptoms get worse or persist.</p>

<h2>WARNING &amp; PRECAUTIONS</h2>

<p><img src="https://www.netmeds.com/images/content/icons/pregnancy.jpg" /></p>

<p>PREGNANCY</p>

<p>CONTRAINDICATED</p>

<p>ENCORATE ORAL SOLUTION is not recommended for use in pregnant women or if you are planning to have a baby as it can cause birth defects and behavioral/learning problems in the baby. Consult your doctor before taking ENCORATE ORAL SOLUTION.</p>

<p><img src="https://www.netmeds.com/images/content/icons/breastfeeding.jpg" /></p>

<p>BREASTFEEDING</p>

<p>CONSULT YOUR DOCTOR</p>

<p>Inform your doctor if you are breastfeeding before taking ENCORATE ORAL SOLUTION as very little medicine might pass through the breastmilk. Consult your doctor if you can breastfeed or not take the medicine during the treatment.</p>

<p><img src="https://www.netmeds.com/images/content/icons/driving_and_using_machines.jpg" /></p>

<p>DRIVING AND USING MACHINES</p>

<p>USE WITH CAUTION</p>

<p>Do not drive or use machines while taking ENCORATE ORAL SOLUTION as it can make you feel sleepy.</p>

<p><img src="https://www.netmeds.com/images/content/icons/alcohol.jpg" /></p>

<p>ALCOHOL</p>

<p>CONTRAINDICATED</p>

<p>Do not consume alcohol while taking ENCORATE ORAL SOLUTION as it can worsen the side effects.</p>

<p><img src="https://www.netmeds.com/images/content/icons/kidney.jpg" /></p>

<p>KIDNEY</p>

<p>USE WITH CAUTION</p>

<p>ENCORATE ORAL SOLUTION should be used with caution in patients with kidney disease. Consult your doctor before taking ENCORATE ORAL SOLUTION.</p>

<p><img src="https://www.netmeds.com/images/content/icons/liver.jpg" /></p>

<p>LIVER</p>

<p>CONTRAINDICATED</p>

<p>ENCORATE ORAL SOLUTION is not recommended for use in patients with liver problems or with a family history of liver disease. Consult your doctor before taking ENCORATE ORAL SOLUTION.</p>

<p><img src="https://www.netmeds.com/images/content/icons/allergy.jpg" /></p>

<p>ALLERGY</p>

<p>CONTRAINDICATED</p>

<p>Do not take ENCORATE ORAL SOLUTION if you are allergic to Sodium valproate or any other ingredients of this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/use_in_pediatrics.jpg" /></p>

<p>USE IN PEDIATRICS</p>

<p>USE WITH CAUTION</p>

<p>ENCORATE ORAL SOLUTION should be used with caution by children. Consult your doctor for advice.</p>

<p><img src="https://www.netmeds.com/images/content/icons/use_in_geriatrics.jpg" /></p>

<p>USE IN GERIATRICS</p>

<p>USE WITH CAUTION</p>

<p>ENCORATE ORAL SOLUTION should be used with caution by the elderly. Consult your doctor for advice.</p>

<h2>OTHERS</h2>

<p>ENCORATE ORAL SOLUTION is not recommended for use if you:</p>

<ul>
<li>Have a rare illness called porphyria which affects metabolism</li>
<li>Have a known metabolic disorder, i.e., a urea cycle disorder</li>
<li>Have a genetic problem caused by a mitochondrial disorder (Alpers-Huttenlocher syndrome)</li>
<li>Are a woman of birth-giving age and not using contraceptives (birth control)</li>
</ul>

<p>Before taking ENCORATE ORAL SOLUTION, inform your doctor if you:</p>

<ul>
<li>Have diabetes</li>
<li>Have a carnitine palmitoyl transferase type II deficiency</li>
<li>Have a brain disease or a metabolic condition affecting the brain</li>
<li>Have a &lsquo;urea cycle disorder&rsquo; where too much ammonia builds up in the body</li>
<li>Have an illness called systemic lupus erythematosus (SLE) (an immune system which affects skin, bones, joints and internal organs)</li>
<li>Genetic problem caused by a mitochondrial disorder in your family</li>
</ul>

<h2>INTERACTIONS</h2>

<p><strong>A. Drug-Drug interactions:</strong></p>

<p>Before taking ENCORATE ORAL SOLUTION, inform your doctor if you are taking any of the following medicine:</p>

<ul>
<li>Medicines used for pain and inflammation (salicylates) (Ex. aspirin)</li>
<li>Other medicines used to treat fits (Ex. phenobarbital, primidone, phenytoin, carbamazepine, rufinamide, topiramate, acetazolamide, lamotrigine and felbamate)</li>
<li>Medicines used for thinning the blood (Ex. warfarin)</li>
<li>Zidovudine, lopinavir and ritonavir (to treat HIV infection)</li>
<li>Temozolomide (to treat cancer)</li>
<li>Medicines for depression (monoamine oxidase inhibitors (MAOI) such as moclobemide, selegiline, linezolid)</li>
<li>Medicines used to calm emotional and mental health problems (Ex. quetiapine, diazepam and olanzapine)</li>
<li>Nimodipine (to treat hemorrhage)</li>
<li>Propofol (used for anesthesia)</li>
<li>Oestrogen-containing products (including some birth control pills)</li>
<li>Medicines to treat malaria (Ex. mefloquine and chloroquine)</li>
<li>Cimetidine (for stomach ulcers)</li>
<li>Carbapenem agents (antibiotics used to treat bacterial infections) Ex. imipenem, meropenem, rifampicin and erythromycin</li>
<li>Cholestyramine used to lower blood fat (cholesterol) levels</li>
<li>Metamizole, (to treat pain and fever)</li>
</ul>

<p><strong>Overdosage:</strong></p>

<p>If you or anyone else accidentally take too much of ENCORATE ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling sick or being sick, pupils of the eye becoming smaller, dizziness, loss of consciousness, weak muscles and poor reflexes, breathing problems, headaches fits (seizures), confusion, memory loss and unusual or inappropriate behavior, shortness of breath and chest pain.</p>

<h2>SYNOPSIS</h2>

<table border="0" cellpadding="1" cellspacing="1">
<tbody>
<tr>
<td><strong>Drug</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Sodium Valproate</td>
</tr>
<tr>
<td><strong>Pharmacological Category</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Anti-convulsant</td>
</tr>
<tr>
<td><strong>Therapeutic Indication</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Epilepsy (fits)</td>
</tr>
<tr>
<td><strong>Dosage Forms</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Tablet, Injection, Syrup, Oral solution, Granules</td>
</tr>
</tbody>
</table>

<h2>MORE INFORMATION</h2>

<ul>
<li>Keep ENCORATE ORAL SOLUTION out of reach from children</li>
<li>Store at room temperature</li>
</ul>

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