<p>&nbsp;</p>

<p>BREASTFEEDING</p>

<p>AMITONE PLUS TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking AMITONE PLUS TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/driving_and_using_machines.jpg" /></p>

<p>DRIVING AND USING MACHINES</p>

<p>Do not drive or operate any machines if you experience dizziness, sedation, reduction in mental alertness after taking AMITONE PLUS TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/alcohol.jpg" /></p>

<p>ALCOHOL</p>

<p>Avoid alcohol consumption while taking AMITONE PLUS TABLET as it may increase the risk of side effects such as sedation and CNS depression. Before taking AMITONE PLUS TABLET inform your doctor if you are having alcohol addiction or abuse.</p>

<p><img src="https://www.netmeds.com/images/content/icons/kidney.jpg" /></p>

<p>KIDNEY</p>

<p>AMITONE PLUS TABLET should be taken with caution in patients with kidney disease. Consult your doctor before taking AMITONE PLUS TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/liver.jpg" /></p>

<p>LIVER</p>

<p>It is not recommended to take AMITONE PLUS TABLET if you have severe liver disease. It should be taken with caution in patients with liver disease. Consult your doctor before taking AMITONE PLUS TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/allergy.jpg" /></p>

<p>ALLERGY</p>

<p>Do not take AMITONE PLUS TABLET if you are allergic to Amitriptyline, Chlordiazepoxide or any other ingredients in this medicine.</p>

<p><img src="https://www.netmeds.com/images/content/icons/lungs.jpg" /></p>

<p>LUNGS</p>

<p>It is not recommended to take AMITONE PLUS TABLET if you have lung disease or you have breathing difficulties while awake or asleep. Consult your doctor before taking AMITONE PLUS TABLET.</p>

<p><img src="https://www.netmeds.com/images/content/icons/heart_disease.jpg" /></p>

<p>HEART DISEASE</p>

<p>[GNKEYWORD] is not recommended for use in patients with recent heart attack, any degree of heart block or disorders of cardiac rhythm and coronary artery insufficiency. It should be taken with caution in patients with slow heart rate, uncompensated heart failure or any cardiovascular disease. Consult your doctor before taking AMITONE PLUS TABLET.</p>

<h2>OTHERS</h2>

<p>AMITONE PLUS TABLET is not recommended for use if you:&nbsp;</p>

<ul>
<li>Have myasthenia gravis (a condition in which the muscles become weak and tire easily)</li>
<li>Have psychiatric illness or a personality disorder (severe mental problems)</li>
<li>Have spinal or cerebral ataxia (balance issues)</li>
</ul>

<p>Before taking AMITONE PLUS TABLET, inform your doctor if you:</p>

<ul>
<li>Have a personal or family history of suicide, bipolar disorder or depression</li>
<li>Electrolyte disturbances</li>
<li>Have convulsive disorders</li>
<li>Have urinary disorders or prostatic hypertrophy</li>
<li>Have hyperthyroidism</li>
<li>Have pylorus stenosis and paralytic ileus</li>
<li>Have symptoms of paranoid</li>
<li>History of drug addiction</li>
<li>Eye diseases</li>
<li>Have schedule for any planned surgery</li>
<li>Receiving electroconvulsive therapy (ECT- treatment to relieve symptoms of mental disturbances)</li>
</ul>

<p><strong>Use in paediatrics</strong></p>

<p>AMITONE PLUS TABLET is not recommended to be given for children and adolescents below 18 years of age due to the lack of safety data. Consult your child&rsquo;s doctor for advice.</p>

<p><strong>Use in geriatrics:</strong></p>

<p>AMITONE PLUS TABLET should be taken with caution in elderly patients due to the risk of developing ataxia, oversedation, confusion or anticholinergic effects (such as dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, increased heart rate and decreased sweating). Consult your doctor before taking AMITONE PLUS TABLET.</p>

<h2>INTERACTIONS</h2>

<p><strong>A.</strong>&nbsp;<strong>Drug-Drug Interactions:</strong></p>

<p>Before taking AMITONE PLUS TABLET, inform your doctor if you are taking any of the following medicines:</p>

<ul>
<li>Topiramate (medicine used to treat fits)</li>
<li>Opioids (medicines used to relieve pain Ex. morphine, codeine)</li>
<li>Quinidine (used to treat malaria)</li>
<li>Cimetidine (used to treat acidity and stomach ulcer)</li>
<li>Phenothiazines (medicines used to treat mental disorders Ex. chlorpromazine, fluphenazine)</li>
<li>Antiarrhythmic medicines (medicines used to treat heart diseases Ex. propafenone and flecainide)</li>
<li>Selective serotonin reuptake inhibitors (SSRIs) (medicines used to treat depression Ex. fluoxetine, sertraline and paroxetine)</li>
<li>Tranylcypromine (used to treat depression)</li>
<li>Selegiline (medicine used to treat parkinson&rsquo;s disease)</li>
</ul>

<p><strong>Overdosage:</strong></p>

<p>If you or anyone else accidentally takes too much of AMITONE PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of AMITONE PLUS TABLET includes confusion, disturbed concentration, transient visual hallucinations, dilated pupils, agitation, hyperactive reflexes, stupor (insensibility), drowsiness, muscle rigidity, vomiting, hypothermia, hyperpyrexia and respiratory depression (in severe cases), fits, fall in blood pressure and coma.</p>

<h2>SYNOPSIS</h2>

<table border="0" cellpadding="1" cellspacing="1">
<tbody>
<tr>
<td><strong>Drug</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Amitriptyline, Chlordiazepoxide</td>
</tr>
<tr>
<td><strong>Pharmacological Category</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Tricyclic antidepressants, Benzodiazepines</td>
</tr>
<tr>
<td><strong>Therapeutic Indication</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Moderate to severe depression and anxiety</td>
</tr>
<tr>
<td><strong>Dosage Forms</strong></td>
<td>:&nbsp;&nbsp;</td>
<td>Capsule, Tablet</td>
</tr>
</tbody>
</table>

<h2>MORE INFORMATION</h2>

<ul>
<li>Keep AMITONE PLUS TABLET out of reach of children</li>
<li>Store at room temperature &nbsp;</li>
</ul>

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