ACILOC contains Ranitidine which belongs to a group of medicines called H2 receptor antagonists. It acts by reducing the amount of acid produced in your stomach. It is used for the treatment and prevention of ulcers of stomach and intestine. It also heals and stop problems caused by heartburn (acid in the food pipe) or indigestion. Ranitidine reduces the secretion of gastric acid stimulated either by food or drugs like non-steroidal anti-inflammatories (NSAIDs), often used to treat arthritis. It reduces gastric acid production by reversibly binding to histamine (H2) receptors present in the lining of gastric parietal cells.

Along with this treatment, your doctor might recommend you, to take enough rest and drink plenty of fluids. Sticking to simple meals and avoiding rich or spicy food can also be beneficial. Avoid smoking and consumption of alcohol during this therapy, as it may reduce the chances of healing and worsen the ulcers. The most common side effects of taking this medicine are stomach pain, constipation or nausea, although not everybody gets them. Before taking this medicine, inform your doctor if you have stomach cancer, kidney problems, porphyria or diabetes. ACILOC should not be taken during pregnancy or while breast-feeding unless considered essential by your doctor.

USES OF ACILOC


Used in the treatment of stomach and duodenal ulcers, heartburn (acid in the food pipe) and indigestion in both adults and in children above 3 years of age
Stops acid reflux, while under anesthesia during an operation


HOW ACILOC WORKS

Ranitidine causes reversible binding to histamine (H2) receptors present in the lining of gastric parietal cells. Binding of histamine to H2 receptors triggers the production of stomach pain. Ranitidine selectively and competitively antagonizes the effects of histamine at H2-receptors and reduces the secretion of gastric acid.

DIRECTIONS FOR USE

Always take this medicine as directed by your physician. Shake well before use. This medicine can be taken with or without food. Your doctor will decide the correct dose and duration of therapy depending upon your age, weight and disease condition.

SIDE EFFECTS OF ACILOC

SERIOUS


Allergic reactions (such as skin rash, flaking skin, swelling of the face, eyelids, lips, mouth or tongue, fever, sudden wheezing, fluttering or tightness of the chest, chest pain, feeling faint or collapse)
A change in the amount of urine passed and its colour
Feeling confused
Slow or irregular heartbeats
Feeling unusually tired
Red or purple spots or skin rash


COMMON


Stomach pain
Constipation
Feeling sick (nausea)


HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea):

Try taking this medicine with, or just after, a meal. Stick to simple meals. Do not eat rich or spicy food.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

PREGNANCY

ACILOC should be used with caution if you are pregnant, or if you are trying to become pregnant. Consult your doctor for advice.

BREASTFEEDING

ACILOC should be used with caution if you are breastfeeding. Consult your doctor for advice.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

KIDNEY

ACILOC should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic (hypersensitive) to ranitidine.

OTHERS

Before taking this medicine, inform your doctor if you:


Have stomach cancer, porphyria, long term breathing problems, diabetes or any problems with your immune system


INTERACTIONS

Talk to your doctor, if you are taking:


Medicines used for pain and swelling (including arthritis) such as indometacin or aspirin
Medicines used to treat diabetes (e.g. glipizide or glibenclamide)
Medicines used to treat heart problems (e.g. procainamide, N-acetylprocainamide or propranolol)
Medicines used to induce sleep (e.g. triazolam or midazolam)
Medicines used to treat infections (e.g. raltegravir, atazanavir, delavirdine, ketoconazole, itraconazole or cefpodoxime)
Medicines used to treat cancer (e.g. erlotinib, gefitinib or lapatinib)
Warfarin (used to stop blood clots)
Lidocaine (a local anaesthetic)
Diazepam (used to treat anxiety)
Phenytoin (used to treat epilepsy)
Theophylline (used to treat long term breathing problems)
Sucralfate (used for stomach ulcers)


SYNOPSIS




Drug
:  
Ranitidine


Pharmacological Category
:  
Histamine H2 Antagonist


Therapeutic Indication
:  

Gastroesophageal reflux disease (GERD), Peptic ulcer disease



Dosage Forms
:  
Tablet, Syrup, Injection




MORE INFORMATION

Store below 20-25°C and keep out of reach of children.