<p>Acenext Mr Tablet is a combination drug that belongs to NSAIDs (non-steroidal anti-inflammatory drugs) or pain killers primarily used for pain relief and muscle relaxation. Muscle pain (myalgia) is widespread and generally refers to uncomfortable sensations in the muscles which can be due to illness, injury or excessive exercise. It can be continuous or can also occur at intervals.</p>
<p> </p>
<p>Acenext Mr Tablet contains three medicines, namely: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever) and Chlorzoxazone (muscle relaxant). Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.</p>
<p> </p>
<p>Acenext Mr Tablet can be taken with or without food as advised by your doctor for the best results. Do not stop taking Acenext Mr Tablet even if you feel better to avoid any unpleasant side effects. Common side effects of Acenext Mr Tablet include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. If any of these side effects get worse or do not subside, please visit your doctor immediately.</p>
<p> </p>
<p>Acenext Mr Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Acenext Mr Tablet as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.</p>
<h2> </h2>
<h2>Uses of Acenext Mr Tablet</h2>
<p> </p>
<p>Musculoskeletal pain</p>
<h2> </h2>
<h2>Medicinal Benefits</h2>
<p> </p>
<p>Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.</p>
<h2> </h2>
<h2>Directions for Use</h2>
<p> </p>
<p>Take Acenext Mr Tablet as advised by your doctor. Preferably take it with a meal to avoid the upset of stomach. Swallow it as a whole, do not chew or crush it. Keep this medicine out of sight and reach of children.</p>
<h2> </h2>
<h2>Storage</h2>
<p> </p>
<p>Store in a cool and dry place away from sunlight</p>
<h2> </h2>
<h2>Side Effects of Acenext Mr Tablet</h2>
<ul>
<li>Nausea</li>
<li>Vomiting</li>
<li>Heartburn</li>
<li>Stomach pain</li>
<li>Diarrhoea</li>
<li>Loss of appetite</li>
<li>Tiredness</li>
<li>Sleepiness</li>
</ul>
<h2> </h2>
<h2>In-Depth Precautions and Warning</h2>
<h3> </h3>
<h3>Drug Warnings</h3>
<p>Acenext Mr Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Acenext Mr Tablet as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.</p>
<h3> </h3>
<h3>Drug Interactions</h3>
<p> </p>
<p><strong>Drug-Drug Interactions: </strong>Acenext Mr Tablet interacts with sleeping pills (alprazolam, escitalopram, zolpidem), pain killers (tramadol, oxycodone, hydrocodone), antiepileptics or medicines for fits (gabapentin, topiramate, pregabalin), diuretics or water pills (fluoxetine), an antidepressant (duloxetine), antiallergic (diphenhydramine, cetirizine), muscle relaxant and antispasmodic (baclofen).</p>
<p> </p>
<p><strong>Drug-Food Interactions: </strong>St. John's wort (a herbal supplement) used as an antidepressant can interact with Acenext Mr Tablet and cause dizziness, so its usage should be avoided with Acenext Mr Tablet.</p>
<p> </p>
<p><strong>Drug-Disease Interactions: </strong>People with alcoholism, liver disease, kidney disease, stomach ulcer/bleeding, and intestinal ulcer/bleeding should avoid using Acenext Mr Tablet.</p>
<p> </p>
<p>Drug-Drug Interactions Checker List:</p>
<ul>
<li>ALPRAZOLAM</li>
<li>ESCITALOPRAM</li>
<li>ZOLPIDEM</li>
<li>TRAMADOL</li>
<li>OXYCODONE</li>
<li>GABAPENTIN</li>
<li>TOPIRAMATE</li>
<li>PREGABALIN</li>
<li>FLUOXETINE</li>
<li>DULOXETINE</li>
<li>DIPHENHYDRAMINE</li>
<li>CETIRIZINE</li>
<li>BACLOFEN</li>
</ul>
<h3> </h3>
<h3>Safety Advice</h3>
<ul>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/alcohal.svg" style="height:38px; width:28px" /></p>
<p>ALCOHOL</p>
UNSAFE
<p>Acenext Mr Tablet with alcohol can cause liver problems, so should not be taken until prescribed if you are taking alcohol.</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/pregnancy.svg" style="height:38px; width:28px" /></p>
<p>PREGNANCY</p>
SAFE IF PRESCRIBED
<p>Only consume Acenext Mr Tablet, if you are prescribed by a doctor.</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/breast-feeding.svg" style="height:38px; width:28px" /></p>
<p>BREAST FEEDING</p>
SAFE IF PRESCRIBED
<p>Only consume Acenext Mr Tablet, if you are prescribed by a doctor</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/driving.svg" style="height:38px; width:28px" /></p>
<p>DRIVING</p>
UNSAFE
<p>Acenext Mr Tablet can impair the ability to drive. So, do not drive or operate heavy machinery that required mental alertness after taking Acenext Mr Tablet.</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/liver.svg" style="height:38px; width:28px" /></p>
<p>LIVER</p>
CAUTION
<p>Acenext Mr Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/kidney.svg" style="height:38px; width:28px" /></p>
<p>KIDNEY</p>
CAUTION
<p>Acenext Mr Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.</p>
</li>
<li>
<p><img alt="Safety Warning" src="https://images.apollo247.in/images/medicine/after-for-children-below-12years.png" style="height:38px; width:28px" /></p>
<p>CHILDREN</p>
SAFE IF PRESCRIBED
<p>Acenext Mr Tablet is not recommended for children below the age of 10 years. The safety and effectivenss of Acenext Mr Tablet has not been established in children due to limited testing of this drug on children by competent authorities across the world.</p>
</li>
</ul>
<h3> </h3>
<h3>Habit Forming</h3>
<p>No</p>
<h3> </h3>
<h3>Diet & Lifestyle Advise</h3>
<ul>
<li>Try to increase the consumption of calcium and vitamin D, as recommended as part of a healthy bone diet.</li>
<li>Omega 3 fatty acid oils enriched food should include in your daily meal for keeping joints healthy.</li>
<li>Connective tissues are the “cellular glue” that connects and support vital organs in the body. This connective tissue is comprised of proteins like collagen and elastin. So the requirement of proteins are required for keeping your muscle healthy, so intake of high protein diets like fish (salmon, sardines, and tuna), chicken, and eggs for non-vegetarian. While legumes, nuts, seed and dairy items (milk, yoghurt, cheese) for a vegetarian person is recommended. </li>
<li>Magnesium, Vitamin K and Zinc enriched foods can help in keeping your bones and muscle healthy so its intake should be enhanced in your daily diet plan. </li>
<li>Physical activities like Tai chi, Yoga, swimming and walking have shown improvement in managing muscle pain. </li>
<li>Do not sit for a longer duration. Try to take a gap of 10 minutes by brisk walking or stretching.</li>
</ul>
