CLIFACE GEL is a combination of Clindamycin and Nicotinamide which belongs to a group of medicines called Lincomycin antibiotics and Vitamin B3 complex, respectively. CLIFACE GEL is used to treat mild to moderate acne which is a skin condition that occurs when hair follicles become plugged with oil and dead skin cells which may occur due to variety of causes such as genetics, fluctuating hormone levels, stress, high humidity or using oily or greasy personal care products which may affect people of all ages.

It is characterized by symptoms such as open or closed plugged pores, small red & tender bumps, pimples, large, solid or painful lumps under the skin and painful & pus-filled lumps under the skin.

Before using CLIFACE GEL inform your doctor if you have liver, kidney, lung or heart diseases. Avoid applying CLIFACE GEL to a cut, scrapped, sunburnt or eczema affected skin.

CLIFACE GEL should be used with caution in pregnant and in breastfeeding women. CLIFACE GEL is not recommended for use in children and adolescents (below 12 years). Consult your doctor before applying.

The most common side effects of using CLIFACE GEL are skin inflammation, contact dermatitis (red, itchy rash), inflammation of hair follicles, itchy skin, dry skin and peeling of skin. Consult your doctor if any of these symptoms worsen.

USES OF CLIFACE GEL

• Treats mild to moderate acne

HOW CLIFACE GEL WORKS

CLIFACE GEL helps to treat acne, where Clindamycin reduces free fatty acid concentrations on the skin and suppresses the growth of Propionibacterium acnes (Corynebacterium acnes), a bacteria found in sebaceous glands and follicles and Nicotinamide exerts anti-inflammatory effect in acne and interrupts sebum production.

DIRECTIONS FOR USE

Apply CLIFACE GEL as advised by your physician. It is for external use only. Before applying the medicine normally wash and dry the affected area and apply a thin layer of this medicine on the affected area. Treated areas on the face need not be covered with a plaster or bandage. Do not apply this medicine beyond the recommended duration. Avoid applying CLIFACE GEL around your eyes, including eyelids. Rinse it off with water if you accidentally get it in these areas.

SIDE EFFECTS OF CLIFACE GEL

COMMON

• Contact dermatitis (red, itchy rash)
• Inflammation of hair follicles
• Itchy skin
• Dry skin
• Peeling of skin

HOW TO MANAGE SIDE EFFECTS

Skin rash/Itchy skin:

Avoid hot bath because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin and apply calamine lotion as a coolant. Discuss with your doctor if the symptom worsens.

WARNING & PRECAUTIONS

PREGNANCY

CLIFACE GEL should be used with caution in pregnant women. Consult your doctor before applying.

BREASTFEEDING

CLIFACE GEL should be used with caution in breastfeeding women. Consult your doctor before applying.

ALLERGY

CLIFACE GEL is not recommended for use if you are allergic to Clindamycin, Nicotinamide or any other ingredients of this medicine.

OTHERS

CLIFACE GEL is not recommended for use if you have:

• Eczema (skin inflammation)
• Cut, scrapped, sunburnt skin

Use in Pediatrics:

CLIFACE GEL is not recommended for use in children and adolescents (below 12 years). Consult your doctor before using it for your child.

Use in Geriatrics:

There is no information on the use of CLIFACE GEL in elderly patients. Consult with your doctor before using.

INTERACTIONS

A. Drug - Drug interactions:

Before using CLIFACE GEL, inform your doctor if you are taking any of the following medicines:

• Acepromazine (used a sedative/tranquilizer)
• Acetaminophen (used to treat pain and inflammation)

Overdosage:

If you or anyone else accidentally ingests or applies too much of CLIFACE GEL, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep CLIFACE GEL out of reach of children
• Store CLIFACE GEL at a temperature below 25°C